/* Layout: a clinical report sheet. 12-column grid, hairline rules, one AGP-style glucose chart as the hero instrument,
   one drawn cross-section of the patch in skin. Cool silicone-grey paper, graphite ink, and pharmacy-vial amber used only
   for the dose (doses, the dose needles, the dose button). Glucose bands use the standard AGP report colours. */
:root {
  --paper: #eff2f1;
  --sheet: #ffffff;
  --ink: #15191c;
  --muted: #59646b;
  --rule: #d2d9db;
  --rule-strong: #aab4b8;
  --dose: #d2690f;
  --dose-ink: #9a4806;
  --dose-tint: #f6e4d1;
  --range: #e1ece5;
  --skin-1: #f3e2d6;
  --skin-2: #ecd2c1;
  --skin-3: #e6c5b2;
  --vlow: #8e1b1b;
  --low: #d23f3f;
  --ok: #3b8a63;
  --high: #e3b23c;
  --vhigh: #c97a26;
  --display: "Schibsted Grotesk", "Helvetica Neue", Arial, sans-serif;
  --body: "IBM Plex Sans", "Helvetica Neue", Arial, sans-serif;
  --mono: "IBM Plex Mono", ui-monospace, Menlo, Consolas, monospace;
  --gutter: 16px;
  --section: 72px;
  --ease: cubic-bezier(.2, .7, .2, 1);
  color-scheme: light;
}
@media (prefers-color-scheme: dark) {
  :root:not([data-theme="light"]) {
    --paper: #0f1314; --sheet: #161b1d; --ink: #e6ebec; --muted: #9aa6ab; --rule: #273034; --rule-strong: #3d494e;
    --dose: #f08a2c; --dose-ink: #f5a55a; --dose-tint: #3a2512; --range: #17271f;
    --skin-1: #3a2b24; --skin-2: #33241e; --skin-3: #2c1f1a;
    --vlow: #e06a6a; --low: #ef6b6b; --ok: #5fb68a; --high: #e8c060; --vhigh: #e0954a;
    color-scheme: dark;
  }
}
:root[data-theme="dark"] {
  --paper: #0f1314; --sheet: #161b1d; --ink: #e6ebec; --muted: #9aa6ab; --rule: #273034; --rule-strong: #3d494e;
  --dose: #f08a2c; --dose-ink: #f5a55a; --dose-tint: #3a2512; --range: #17271f;
  --skin-1: #3a2b24; --skin-2: #33241e; --skin-3: #2c1f1a;
  --vlow: #e06a6a; --low: #ef6b6b; --ok: #5fb68a; --high: #e8c060; --vhigh: #e0954a;
  color-scheme: dark;
}
@media (min-width: 760px) { :root { --gutter: 32px; --section: 112px; } }

* { box-sizing: border-box; }
[hidden] { display: none !important; }
html { -webkit-text-size-adjust: 100%; scroll-behavior: smooth; }
body { margin: 0; background: var(--paper); color: var(--ink); font: 400 16px/1.6 var(--body); -webkit-font-smoothing: antialiased; }
h1, h2, h3, p, ul, ol, dl, dd, figure { margin: 0; }
ul, ol { padding: 0; list-style: none; }
a { color: inherit; }
:focus-visible { outline: 2px solid var(--ink); outline-offset: 3px; }
.wrap { max-width: 1240px; margin-inline: auto; padding-inline: var(--gutter); }
.grid { display: grid; grid-template-columns: repeat(12, minmax(0, 1fr)); column-gap: 24px; row-gap: 32px; }
.grid > * { grid-column: 1 / -1; min-width: 0; }

/* Type scale: 12 / 14 / 16 / 18 / 24 / 32 / 48-60 */
.label { font: 500 12px/1.4 var(--mono); text-transform: uppercase; letter-spacing: .08em; color: var(--muted); }
.h1 { font: 500 clamp(38px, 5.2vw, 64px)/1.02 var(--display); letter-spacing: -.025em; text-wrap: balance; }
.h2 { font: 500 clamp(28px, 3.4vw, 40px)/1.08 var(--display); letter-spacing: -.02em; text-wrap: balance; }
.h3 { font: 600 18px/1.3 var(--display); letter-spacing: -.005em; }
.lead { font-size: 18px; line-height: 1.6; max-width: 36em; color: var(--ink); }
.muted { color: var(--muted); }
.mono { font-family: var(--mono); }
.num { font-variant-numeric: tabular-nums; }
.dose-word { color: var(--dose-ink); }
sup.ref { font: 500 10px/1 var(--mono); }
sup.ref a { text-decoration: none; color: var(--muted); padding-inline: 1px; }
sup.ref a:hover { color: var(--ink); }
sup.ref a + a::before { content: ","; color: var(--muted); }

/* Buttons */
.btn {
  display: inline-flex; align-items: center; gap: 10px; font: 500 15px/1 var(--body); text-decoration: none;
  padding: 14px 20px; border-radius: 999px; border: 1px solid var(--ink); color: var(--ink); background: transparent;
  transition: background .2s var(--ease), color .2s var(--ease);
}
.btn:hover { background: var(--ink); color: var(--paper); }
.btn.primary { background: var(--ink); color: var(--paper); }
.btn.primary:hover { background: var(--dose); border-color: var(--dose); color: #fff; }
.btn .arr { font-family: var(--mono); }

/* Nav */
.nav { position: sticky; top: env(safe-area-inset-top, 0px); z-index: 10; background: color-mix(in srgb, var(--paper) 88%, transparent); backdrop-filter: blur(8px); -webkit-backdrop-filter: blur(8px); border-bottom: 1px solid var(--rule); }
.nav .wrap { display: flex; align-items: center; justify-content: space-between; gap: 16px; height: 60px; }
.brand { display: inline-flex; align-items: center; gap: 10px; text-decoration: none; font: 600 19px/1 var(--display); letter-spacing: -.02em; }
.brand svg { width: 24px; height: 24px; flex: none; }
.nav ul { display: flex; gap: 26px; font-size: 14px; }
.nav ul a { text-decoration: none; color: var(--muted); }
.nav ul a:hover { color: var(--ink); }
.nav .btn { padding: 9px 14px; font-size: 14px; }
@media (max-width: 860px) { .nav ul { display: none; } }

/* Sections */
section.block { padding-block: var(--section); border-top: 1px solid var(--rule); }
.sec-head { display: grid; gap: 14px; }
@media (min-width: 1000px) {
  .sec-head { grid-column: 1 / span 5; align-self: start; position: sticky; top: calc(env(safe-area-inset-top, 0px) + 92px); padding-right: 24px; }
  .sec-body { grid-column: 6 / span 7; }
}

/* Evidence table */
.tbl-wrap { overflow-x: auto; border-top: 1px solid var(--ink); }
table { width: 100%; border-collapse: collapse; font-size: 15px; min-width: 640px; }
th, td { text-align: left; vertical-align: top; padding: 14px 16px 14px 0; border-bottom: 1px solid var(--rule); }
th { font: 500 11px/1.4 var(--mono); text-transform: uppercase; letter-spacing: .08em; color: var(--muted); padding-top: 12px; }
td:first-child { font-weight: 500; width: 28%; }
td .muted { font-size: 14px; }
.pill { display: inline-flex; align-items: center; gap: 6px; font: 500 11px/1 var(--mono); white-space: nowrap; padding: 5px 8px 5px 7px; border-radius: 999px; border: 1px solid currentColor; }
.pill::before { content: ""; width: 6px; height: 6px; border-radius: 50%; background: currentColor; }
.pill.market { color: var(--ok); }
.pill.trial { color: var(--vhigh); }
.pill.lab { color: var(--muted); }
.pill.none { color: var(--dose-ink); }

/* Closing */
.closing { padding-block: var(--section); border-top: 1px solid var(--rule); }
.closing .inner { display: grid; gap: 22px; justify-items: start; max-width: 760px; }
footer { border-top: 1px solid var(--rule); padding-block: 28px 40px; font-size: 13px; color: var(--muted); }
footer .wrap { display: flex; flex-wrap: wrap; gap: 12px 32px; justify-content: space-between; }
footer p { max-width: 52em; }